About the Clinical Trials

RECOVER brings together patients, caregivers, doctors, community leaders, and researchers to better understand Long COVID.

The National Institutes of Health (NIH) created the RECOVER Initiative to learn about the long-term effects of COVID. RECOVER researchers across the country are looking for answers about how and why Long COVID affects people differently.

RECOVER clinical trials are designed as platform protocols that allow researchers to study different interventions, or possible treatments, at the same time.

Learn more about the design of the clinical trials

Focus Areas

The RECOVER clinical trials focus on these symptom areas that Long COVID patients have reported to be the most burdensome and important to address:

  • Autonomic Dysfunction: dizziness, fast heart rate, shortness of breath, upset stomach, or other changes in body functions that happen automatically
  • Cognitive Dysfunction: brain fog, trouble thinking clearly, memory changes, slowed attention, and other symptoms related to brain function
  • Exercise Intolerance and Fatigue: exhaustion or low energy that interferes with daily activities
  • Sleep Disturbances: changes in sleep patterns or ability to sleep
  • Viral Persistence: when the virus that causes COVID-19 stays in the body and causes damage to organs or the immune system to not function properly
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