About the Clinical Trials
RECOVER brings together Patient, Caregiver, and Community Representatives, doctors, and researchers to better understand and find possible treatments for Long COVID.
The National Institutes of Health (NIH) created the RECOVER Initiative to understand, treat, and prevent Long COVID. RECOVER researchers across the country are looking for answers about why Long COVID affects people differently and how to treat it.
RECOVER clinical trials are designed as platform protocols that allow researchers to study multiple possible treatments, or study interventions, at the same time. RECOVER’s 8 clinical trials will explore 13 possible treatments for Long COVID symptoms.
Learn more about the design of the clinical trials
Focus Areas
The RECOVER team identified 5 focus areas for clinical trials based on researchers’ learnings from RECOVER observational cohort studies and conversations with people living with Long COVID. RECOVER clinical trials focus on 5 groups of symptoms that Long COVID patients reported to be the most burdensome and important to address:
- Autonomic Dysfunction: dizziness, fast heart rate, shortness of breath, upset stomach, or other changes in body functions that happen automatically
- Cognitive Dysfunction: brain fog, trouble thinking clearly, memory changes, slowed attention, and other symptoms related to brain function
- Exercise Intolerance and Fatigue: exhaustion or low energy that interferes with daily activities
- Sleep Disturbances: changes in sleep patterns or ability to sleep
- Viral Persistence: when the virus that causes COVID-19 stays in the body and causes damage to organs or the immune system to not function properly